The recent publication of FAME in the NEJM drew attention to FFR (fractional flow reserve) to guide PCI during angiography. Now, a new study published online in the American Journal of Cardiology may shed some light on its practical clinical utility. In a study of 142 patients with intermediate LMCA stenosis, the researchers concluded that “FFR measurement is helpful in guiding the decision whether to revascularize patients with intermediate LMCA stenosis. However,
patients with diabetes remain at higher risk, and higher doses than previously recommended of intracoronary adenosine might have to be used in the evaluation of LMCA stenosis.”

You can see the FAME slide set at ClinicalTrialResults.com, where it was originally posted following the initial TCT presentation.

You can also view a video interview with FAME investigator Nico Pijls by C. Michael Gibson on ClinicalTrialResults.com.