ACC.10 & i2 Summit in Atlanta: Late-Breaking Clinical Trials Reply

Late-Breaking Clinical Trials I: General Cardiology

  • Co-Chairs: Michael H. Crawford, Brian OMurchu
  • Panelists: Friedrich Mohr, Elijah Saunders, Paul D. Thompson

3010-6: Effects of Combination Lipid Therapy on Cardiovascular Events in Type 2 Diabetes Mellitus: The ACCORD Lipid Study

  • Sunday, Mar 14, 2010, 8:00 AM – 8:12 AM
  • Henry Ginsberg, on behalf of The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Group, Columbia University College of Physicians & Surgeons, New York, NY

3010-8: Effects of Intensive Blood Pressure Control on Cardiovascular Events in Type 2 Diabetes Mellitus: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Blood Pressure Trial

  • Sunday, Mar 14, 2010, 8:17 AM – 8:29 AM
  • William C. Cushman, on behalf of The ACCORD Study Group, Veterans Affairs Medical Center, Memphis, TN

3010-10: Rethinking Lower BP Goals for Diabetics with Documented Coronary Artery Disease: Findings from the INternational VErapamil SR – Trandolapril STudy (INVEST)

  • Sunday, Mar 14, 2010, 8:34 AM – 8:46 AM
  • Rhonda M. Cooper-Dehoff, Yan Gong, Eileen M. Handberg, Anthony L. Bavry, Scott J. Denardo, George L. Bakris, Carl J. Pepine, University of Florida, Gainesville, FL

3010-12: The Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial

  • Sunday, Mar 14, 2010, 8:51 AM – 9:03 AM
  • Robert M. Califf, Rury A. Holman, John J. McMurray, Steven M. Haffner, The NAVIGATOR Study Group, Duke Clinical Research Institute, Durham, NC, Diabetes Trial Unit, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom

3010-14: Primary Safety and Efficacy Endpoints of the EVEREST II Randomized Clinical Trial

  • Sunday, Mar 14, 2010, 9:08 AM – 9:20 AM
  • Ted Feldman, Laura Mauri, Elyse Foster, Donald Glower, The EVEREST II Investigators, Evanston Hospital, Evanston, IL

Late-Breaking Clinical Trials II: Cardiac Arrhythmias

  • Monday, Mar 15, 2010, 8:00 AM – 9:30 AM
  • Co-Chairs: Byron K. Lee, Kevin M. Monahan
  • Panelists: A. John Camm, Lars Wallentin, Michel Haissaguerre

3015-6: Cryoballoon Ablation of Pulmonary Veins for Paroxysmal Atrial Fibrillation: First Results of the North American Arctic Front Stop-AF Clinical Trial

  • Monday, Mar 15, 2010, 8:00 AM – 8:12 AM
  • Douglas L. Packer, James M. Irwin, Jean Champagne, Peter G. Guerra, Marc Dubuc, Kevin R. Wheelan, Robert C. Kowal, John W. Lehmann, Richard G. Holcomb, Jeremy N. Ruskin, Mayo Clinic/St. Marys Hospital, Rochester, MN

3015-8: Rate Control Efficacy in Permanent Atrial Fibrillation: a Comparison Between Lenient Versus Strict Rate Control in Patients With and Without Heart Failure. The RACE II Study

  • Monday, Mar 15, 2010, 8:17 AM – 8:29 AM
  • Isabelle C. Van Gelder, MD, Hessel F. Groenveld, Harry J. Crijns, Jan G. Tijssen, Hans J. Hillege, Ype S. Tuininga, Marco Alings, Dirk J. Van Veldhuisen, Maarten P. Van den Berg, University Medical Center Groningen, Groningen, The Netherlands, Interuniversity Cardiology Institute Netherlands, Utrecht, The Netherlands

3015-10: The Impact of Remote Monitoring with Automatic Clinician Notifications on the clinical care of ICD and CRT-D Patients

  • Monday, Mar 15, 2010, 8:34 AM – 8:46 AM
  • George H. Crossley, III, R. Hardwin Meade, Holly S. Vitense, Yanping Chang, Andrew Boyle, St. Thomas Research Institute, Nashville, TN, Sequoia Hospital, Redwood City, CA

3015-12: A Randomized Clinical Trial of Three Doses of a Long-Acting Oral Direct Factor Xa Inhibitor Betrixaban in Patients With Atrial Fibrillation

  • Monday, Mar 15, 2010, 8:51 AM – 9:03 AM
  • Michael D. Ezekowitz, Rafael Diaz, Paul Dorian, Stephen Hohnloser, Sergio Cossu, Ralph Vicari, Jose Teixeira, Eduard Gorina, Daniel Gretler, Uma Sinha, Stuart Connolly, Lankenau Institute for Medical Research, Wynnewood, PA

3015-14: Catheter Ablation vs. Antiarrhythmic Drug Therapy for Atrial Fibrillation: First Results of the CABANA Pilot Study

  • Monday, Mar 15, 2010, 9:08 AM – 9:20 AM
  • Douglas L. Packer, Kerry Lee, Daniel Mark, Kristi Monahan, Kathleen Hoffmann, Gail E. Hafley, Jeanne E. Poole, Tristram D. Bahnson, David J. Bradley, David J. Wilber, John D. Hummel, Steven J. Bailin, John D. Day, Anil K. Bhandari, Francis E. Marchlinski, Neal Kay, Hugh Calkins, William Stevenson, Richard Robb, Maryam Rettmann, David R. Holmes, III, Mayo Clinic, Rochester, MN, Duke Clinical Research Inst., Durham, NC

Late-Breaking Clinical Trials III: Interventional Cardiology

  • Monday, Mar 15, 2010, 10:30 AM -12:00 PM
  • Co-Chairs: George D. Dangas, Patrick L. Whitlow
  • Panelists: Laura Mauri, Harvey D. White, Paul A. Gurbel

3016-06: Randomized All-comer Comparison of Zotarolimus-eluting and Sirolimus-eluting Coronary Stents: 18-month Follow-up in the SORT OUT III Trial

  • Monday, Mar 15, 2010, 10:30 AM -10:40 AM
  • Michael Maeng, Klaus Rasmussen, Anne Kaltoft, Per Thayssen, Anders Galløe, Henning Kelbæk, Hans-Henrik Tilsted, Ulrik Abildgaard, Evald H. Christiansen, Thomas Engstrøm, Lars R. Krusell, Jan Ravkilde, Peter R. Hansen, Knud N. Hansen, Steen Z. Abildstrøm, Jens Aarøe, Jan S. Jensen, Steen D. Kristensen, Hans E. Bøtker, Morten Madsen, Søren P. Johnsen, Lisette O. Jensen, Henrik T. Sørensen, Leif Thuesen, Jens F. Lassen, Aarhus University Hospital, Skejby, Aarhus, Denmark, Aarhus University Hospital, Aalborg, Aalborg, Denmark

3016-08: Randomized Trial of a Polymer-Free Dual Drug-Eluting Stent versus Polymer-Based Cypher and Endeavor Drug-Eluting Stents – Two-year Clinical and Angiographic Outcomes

  • Monday, Mar 15, 2010, 10:48 AM -10:58 AM
  • Robert A. Byrne, Adnan Kastrati, Klaus Tiroch, Stefanie Schulz, Jürgen Pache, Susanne Pinieck, Steffen Massberg, Melchior Seyfarth, Karl-Ludwig Laugwitz, Anette Birkmeier, Albert Schömig, Julinda Mehilli, Deutsches Herzzentrum, Technische Universität, Munich, Germany, 1. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität, Munich, Germany

3016-10: First Report of the PERSEUS Randomized Controlled Trial Comparison of a Novel Platinum-Chromium, Thin-Strut TAXUS Element Stent Versus the TAXUS Express Stent in de novo Coronary Stenoses

  • Monday, Mar 15, 2010, 11:06 AM -11:16 AM
  • Dean J. Kereiakes, Louis A. Cannon, Robert L. Feldman, Gregory J. Mishkel, Abram C. Rabinowitz, Robert Whitbourn, Raymond Magorien, Paul Underwood, Keith D. Dawkins, The Christ Hospital Heart and Vascular Center/The Lindner Center for Research and Education, Cincinnati, OH, Boston Scientific Corporation, Natick, MA

3016-12: Randomized Trial Evaluating the Efficacy of Cilostazol on Ischemic Vascular Complications after Drug-eluting Stent Implantation for Coronary Heart Disease : Influence of Cilostazol-based triple anti-platelet therapy on Ischemic Complication after drug-eluting stent implantation (CILON-T) study

  • Monday, Mar 15, 2010, 11:24 AM -11:34 AM
  • Hyo-Soo Kim, Seung-Pyo Lee, Jung-Won Suh, In-Ho Chae, Seung-Woon Rha, Jang-Ho Bae, Myung-Chan Cho, Cardiovascular Center, Seoul National University Hospital, Seoul, South Korea

3016-14: Optimal Duration of Dual Antiplatelet Therapy After Drug-Eluting Stents Implantation: A Randomized, Multi-Center Trial

  • Monday, Mar 15, 2010, 11:42 AM -11:52 AM
  • Seung-Jung Park, Asan Medical Center, Seoul, South Korea

Late-Breaking Clinical Trials IV

  • Tuesday, Mar 16, 2010, 8:00 AM – 9:30 AM
  • Co-Chairs: Paul J. Mather, Anthony E. Steimle, Mandeep R. Mehra
  • Panelists: J. Scott Millikan, Rita F. Redberg

3019-6: Effect of Genotyping Warfarin Patients on Outcomes: Results from The National Community-based Medco-Mayo Warfarin Effectiveness Study (MM-WES)

  • Tuesday, Mar 16, 2010, 8:00 AM – 8:12 AM
  • Robert S. Epstein, Thomas P. Moyer, J Russell Teagarden, Ronald E. Aubert, Dennis J. O’Kane, Medco Health Solution, Franklin Lakes, NJ, Mayo Clinic, Rochester, MN

3019-8: The Diuretic Optimization Strategies Evaluation (DOSE) Study: A Randomized, Double Blind, Placebo-controlled Trial Of Diuretic Strategies In Acute Decompensated Heart Failure

  • Tuesday, Mar 16, 2010, 8:17 AM – 8:29 AM
  • Gary Michael Felker, for the NHLBI Heart Failure Clinical Research Network, Duke University School of Medicine, Durham, NC

3019-10: Effect of the Direct Renin Inhibitor Aliskiren on Left Ventricular Remodeling Following Myocardial Infarction with Left Ventricular Dysfunction: ASPIRE

  • Tuesday, Mar 16, 2010, 8:34 AM – 8:46 AM
  • Scott D. Solomon, Sung Hee Shin, Amil Shah, Lars Kober, Aldo Maggioni, Jean Rouleau, John J.V. McMurray, Roxzana Kelly, Allen Hester, Marc A. Pfeffer, Brigham and Women’s Hospital, Boston, MA

3019-12: Effects of Clinical Characteristics and Treatments on Gender Difference in Outcomes after Acute Myocardial Infarction: A Propensity Score-Matched Analysis

  • Tuesday, Mar 16, 2010, 8:51 AM – 9:03 AM
  • Francois Schiele, Nicolas F. Meneveau, Marie-France Seronde, Vincent Descotes-Genon, Joanna Dutheil, Romain Chopard, Fiona Ecarnot, Jean-Pierre Bassand, University Hospital Jean Minjoz, Besancon, France

3019-14: Influence of Reduction of Left Ventricular Volume on Outcome After Coronary Artery Bypass Grafting With or Without Surgical Ventricular Reconstruction

  • Tuesday, Mar 16, 2010, 9:08 AM – 9:20 AM
  • Robert E. Michler, Gerald M. Pohost, Krzysztof Wrobel, Robert O. Bonow, Jan Pirk, Jae K. Oh, Carmelo A. Milano, Patricia A. Pellikka, Francois Dagenais, Thomas A. Holly, Anne S. Hellkamp, Kerry L. Lee, Marisa Di Donato, Duke Clinical Research Institute, Durham, NC

Late-Breaking Clinical Trials V: Interventional Cardiology

  • Tuesday, Mar 16, 2010, 10:30 AM -12:00 PM
  • Co-Chairs: Gregg W. Stone, David J. Moliterno
  • Panelists: Gennaro Sardella, William W. O’Neill, Joseph F. Sabik

3020-06: Randomized Comparison of Angiojet Rheolytic Thrombectomy Before Direct Infarct Artery Stenting to Direct Stenting Alone in Patients with Acute Myocardial Infarction: the Jetstent Trial.

  • Tuesday, Mar 16, 2010, 10:30 AM -10:40 AM
  • David Antoniucci, Antonio Colombo, Amerigo Stabile, Alfredo Rodriguez, Franz-Joseph Neumann, Angela Migliorini, Renato Valenti, Division of Cardiology, Careggi Hospital, Florence, Italy

3020-07: Panel Discussion, 10:40 AM -10:48 AM

3020-08: Long-term Outcome after Drug-Eluting versus Bare-Metal Stent Implantation in Patients with ST-Elevation Myocardial Infarction. Three-year follow-up of the DEDICATION Trial

  • Tuesday, Mar 16, 2010, 10:48 AM -10:58 AM
  • Peter Clemmensen, Henning Kelbæk, Anne Kaltoft, Steffen Helqvist, Jens F. Lassen, Lene Kløvgaard, Christian J. Terkelsen, Hans-Henrik Tilsted, Thomas Engstrøm, Lars R. Krusell, Evald H. Christiansen, Kari Saunamäki, Erik Jørgensen, Hans Erik Bøtker, Jan Ravkilde, Klaus F. Kofoed, Lars Køber, Leif Thuesen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, Skejby Hospital, Aarhus University, Aarhus, Denmark

3020-09: Five Year Follow-up After Primary Percutaneous Coronary Intervention With A Paclitaxel-eluting Stent Versus A Bare-metal Stent In Acute ST-segment Elevation Myocardial Infarction. A Follow-up Study Of The PASSION-Trial.

  • Tuesday, Mar 16, 2010, 10:58 AM -11:08 AM
  • Maarten Vink, Maurits Dirksen, Maarten Jan Suttorp, Jan Tijssen, Jeroen Van Etten, Ton Slagboom, Mark Patterson, Ferdinand Kiemeneij, Gert Jan Laarman, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands

3020-11: Ticagrelor Versus Clopidogrel In Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery: Results From The PLATO Trial

  • Tuesday, Mar 16, 2010, 11:23 AM -11:33 AM
  • Claes Held, Jean-Pierre Bassand, Richard C. Becker, Christopher P. Cannon, Marc J. Claeys, Robert A. Harrington, Jay Horrow, Steen Husted, Stefan K. James, Kenneth W. Mahaffey, José C. Nicolau, Sylvia Olofsson, Benjamin M. Scirica, Robert F. Storey, Marius Vintila, Joseph Ycas, Lars Wallentin, Uppsala Clinical Research Center and Department of Cardiology, Uppsala, Sweden, Sweden

3020-13: A Randomized Trial Radial Artery Grafts versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery: VA Cooperative Study

  • Tuesday, Mar 16, 2010, 11:41 AM -11:51 AM
  • Steven Goldman, Gulshan Sethi, William Holman, Hoang Thai, Yvette Rodriguez, Kelvin Lee, CSP 474 Study Group, Southern Arizona VA Health Care System, Tucson, AZ, VA Medical Center Palo Alto, Palo Alto, CA
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