Search Results for: matsubara

Scientific Misconduct: From Darwin And Mendel To Poldermans And Matsubara

Responding to recent episodes of scientific misconduct in cardiovascular research involving once prominent cardiovascular researchers, the editor of the European Heart Journal, Thomas Lüscher, has written an editorial discussing the significance of the new cases and placing them in a historical context that includes allegations of scientific misconduct by Mendel and Darwin, among many others. … Poldermans was the…

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Japanese Research Scandal Involving Novartis Blood Pressure Drug Widens

The Japanese scandal over research using the Novartis blockbuster hypertension drug Diovan (valsartan) continues to widen. The first major figure brought down in the scandal was Hiroaki Matsubara, a prominent cardiologist and researcher at Kyoto Prefectural University in Japan, who  resigned from his position after numerous retractions and investigations. Then last year accusations surfaced about another prominent researcher, Issei Komuro, a professor…

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Lancet Formally Retracts Jikei Heart Study Of Valsartan

The Lancet has formally retracted the Jikei Heart Study paper, originally published in 2007. The retraction had been widely anticipated for more than a month, after a series of news reports in Japan made it clear that the long-simmering controversy over scientific misconduct involving the Novartis blood pressure lowering drug valsartan (Diovan) had come to a full boil. (See our earlier story here.)…

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Diovan Data Was Fabricated, Say Japanese Health Minister And University Officials

Following a long series of accusations, retractions, and the resignation of a prominent professor, it now is clear that data from a large Japanese study of valsartan (Diovan, Novartis) was fabricated. On Thursday officials at Kyoto Prefectural University of Medicine said that “had patient records been used in their entirety,” the Kyoto Heart Study “would have…

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Japanese Research Scandal Expands To A Second Trial And A Novartis Employee

A Japanese research scandal, which has so far centered on actions taken by the once-prominent cardiologist Hiroaki Matsubara, has now expanded. As has been previously reported, several papers authored by Matsubara have been retracted, including, most notably, the main publication of the Kyoto Heart Study in the European Heart Journal. Now, however, questions have been…

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Two Retractions For Embattled Chief Investigator Of Kyoto Heart Study

The editor of Circulation Journal, the official journal of the Japanese Circulation Society (and not to be confused with the American Heart Association’s better known Circulation) has announced the retraction of two substudies from the Kyoto Heart Study. The papers, according to the editor, “contain a number of serious errors in data analysis.” Read my entire…

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2012 In Review: A Bad Year For Conventional Wisdom

This was a really grim year for anyone who thought we had things pretty well figured out. Time and again conventional wisdom was thrown out the window. 2012 forced the cardiology community to reconsider what it thought it knew about HDL cholesterol, platelet function tests, aspirin resistance, triple therapy, IABP, and more. One device company,…

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Prominent Japanese Cardiologist Accused of Scientific Misconduct

Following accusations by independent bloggers in Japan and Germany, the American Heart Association (AHA) has issued an Expression of Concern about five papers published in AHA journals co-authored by Hiroaki Matsubara, a prominent cardiologist and researcher at Kyoto Prefectural University in Japan. In addition to his many papers exploring the basic science of the renin-angiotensin system, Matsubara…

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KYOTO HEART at ESC: have ARBs finally come of age?

Since they first became available almost 15 years ago, ARB supporters have tried to fight the impression that the drugs are nothing more than ACE inhibitors without the cough. The latest effort to do this, the KYOTO HEART study, was presented earlier today at the ESC and published simultaneously in the European Heart Journal….

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Barcelona: List of ESC Hot Lines, Clinical Trial Updates, and Science Hot Lines

Updated and Corrected: The ESC has posted the complete scientific program for the ESC Congress 2009 in Barcelona. Here are the details for Hot Line, Clinical Trial Update, and Science Hot line  sessions. You can access the complete program at this link….

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