Ultrafiltration Fails To Show Benefit In Acute Heart Failure

Although ultrafiltration (UF) in recent years has become increasingly popular as an alternative to intravenous diuretics for patients with acute decompensated heart failure with acute cardiorenal system (type 1), the first clinical trial to test its value shows that it is inferior to standard drug therapy. The results of CARRESS-HF (Cardiorenal Rescue Study in Acute Decompensated…

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RELAX-AHF Stirs Interest In Novel Drug For Acute Heart Failure

A new drug modelled on a hormone active in pregnancy may prove beneficial to patients with acute decompensated heart failure. Serelaxin is a recombinant form of human relaxin-2, which is known to mediate the hemodynamic changes that occur during pregnancy. The drug is under development by Novartis for use in acute heart failure. In the…

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